The project aims to design and development of two new pharmacological formulations based on povidone iodide (PVP-I) in the ophthalmology sector for the prevention and treatment of bacterial, viral and microbial infections which, if not treated adequately and in time, they can also lead to loss of vision. The active ingredient will be conveyed through an innovative micro/nano particle system able to stabilize them in aqueous solution (eye drops), and to improve their bioavailability in ocular tissues as well as ophthalmic tolerability.