{"id":8322,"date":"2023-05-18T20:43:02","date_gmt":"2023-05-18T18:43:02","guid":{"rendered":"http:\/\/150.145.64.139\/?page_id=8322"},"modified":"2023-10-11T09:16:40","modified_gmt":"2023-10-11T07:16:40","slug":"drug-delivery","status":"publish","type":"page","link":"https:\/\/www.ipcf.cnr.it\/it\/research\/drug-delivery\/","title":{"rendered":"Drug Delivery"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"8322\" class=\"elementor elementor-8322\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2bf69cbe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2bf69cbe\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-654da7e5\" data-id=\"654da7e5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6020ad53 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6020ad53\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-349eca6\" data-id=\"349eca6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2dfb1976 elementor-widget elementor-widget-text-editor\" data-id=\"2dfb1976\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div style=\"text-align: justify;\" title=\"Page 11\"><p>The integration of composite functions in one material is a great promise towards personalized nanomedicine, aiming at enhancing the therapeutic efficacy of drugs and avoiding under- or over-treatment of specific diseases. Multi-tasked molecules, as well as self-assembled systems and functionalized nanosized particles are promising candidates for delivering drugs to the biological target. Particular interest is devoted to the study of the physico-chemical properties, structural features and colloidal stability of multi-functionalized vesicles spontaneously formed by amphiphilic macromolecules or of multi-functionalized nanoparticles. Their validation in terms of cell uptake or photodynamic properties (for those species possessing specific chromophores) is also performed by exploiting fluorescence microscopy or the spectroscopic response under light irradiation (oxygen radicals production). The kinetics of the release and the stability of the drug in an environment mimicking the biological target are also investigated.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-13fead3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"13fead3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-dd3117d\" data-id=\"dd3117d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f882f26 elementor-widget elementor-widget-text-editor\" data-id=\"f882f26\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><strong>Labs involved in these research activities<\/strong><\/h5><ul><li><a href=\"http:\/\/www.ipcf.cnr.it\/it\/laboratories\/laboratory-of-light-scattering-and-fluorescence-spectroscopy-for-the-study-of-nanostructured-materials-and-optical-molecular-sensors\/\" target=\"_blank\" rel=\"noopener\">Laboratory of Light Scattering and Fluorescence Spectroscopy\u00a0<\/a><\/li><li><a href=\"http:\/\/www.ipcf.cnr.it\/it\/laboratories\/laboratory-of-production-and-characterization-of-biomaterials-from-macro-to-nanoscale\/\" target=\"_blank\" rel=\"noopener\">Laboratorio di Produzione e Caratterizzazione di Biomateriali dalla Macro alla Nanoscala<\/a><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-68407a9\" data-id=\"68407a9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f78d8ec elementor-widget elementor-widget-text-editor\" data-id=\"f78d8ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><strong>Persone<\/strong><\/h5><ul><li><a href=\"http:\/\/www.ipcf.cnr.it\/it\/team\/valentina-villari\/\" target=\"_blank\" rel=\"noopener\">V. Villari,<\/a> <a href=\"http:\/\/www.ipcf.cnr.it\/it\/team\/norberto-micali\/\" target=\"_blank\" rel=\"noopener\">N. Micali<\/a><\/li><li><a href=\"http:\/\/www.ipcf.cnr.it\/it\/team\/caterina-cristallini\/\" target=\"_blank\" rel=\"noopener\">C. Cristallini<\/a><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>The integration of composite functions in one material is a great promise towards personalized nanomedicine, aiming at enhancing the therapeutic efficacy of drugs and avoiding under- or over-treatment of specific diseases. Multi-tasked molecules, as well as self-assembled systems and functionalized nanosized particles are promising candidates for delivering drugs to the biological target. Particular interest is [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":2303,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-8322","page","type-page","status-publish","hentry"],"aioseo_notices":[],"guten_post_layout_featured_media_urls":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false,"wpca-thumb":false,"guten_post_layout_landscape_large":false,"guten_post_layout_portrait_large":false,"guten_post_layout_square_large":false,"guten_post_layout_landscape":false,"guten_post_layout_portrait":false,"guten_post_layout_square":false,"academix-single-team-thumb":false,"academix-team-thumbnail":false,"academix-event-thumbnail":false,"academix-event-gallery-thumb":false,"academix-blog-thumb":false},"_links":{"self":[{"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/pages\/8322","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/comments?post=8322"}],"version-history":[{"count":19,"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/pages\/8322\/revisions"}],"predecessor-version":[{"id":9928,"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/pages\/8322\/revisions\/9928"}],"up":[{"embeddable":true,"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/pages\/2303"}],"wp:attachment":[{"href":"https:\/\/www.ipcf.cnr.it\/it\/wp-json\/wp\/v2\/media?parent=8322"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}